Sodium Lauryl Sulphate Health and Safety information

Sodium Lauryl Sulphate

Health and Safety Information on the Chemical

Acute Toxicity

Acute toxicity data in the rat show that SLS is harmful by the oral route (LD50 1200 mg/kg bw), and data in the rabbit and guinea pig show it is harmful by the dermal route (LD50 = ~600 mg/kg bw and >1200 mg/kg bw respectively).

Irritation

SLS is a skin and eye irritant in rabbits, and skin irritation has been observed in clinical studies in humans. Indeed in the human 4-hour patch test for irritation, SLS is used at 20% as a positive control to identify substances or preparations that would be on the borderlinefor classification as irritant. SLS is also reported  o irritate the respiratory tract.

Sodium Lauryl Sulphate

Sodium Lauryl Sulphate photo by: Newly Natural

Sodium Lauryl Sulphate

Identification of Petitioned Substance

Chemical Names: Sodium lauryl sulfate (SLS)

Other Names: dodecyl sodium sulfate; dodecyl sulfate; sodium dodecyl sulfate (SDS); sodium n-dodecyl sulfate; Chemfinder (2006) lists many additional names

for SLS

CAS Number: 14 151-21-3

Other Codes: X1001083-4 (ACX number); 1315 (HSDB number); SS110 (IMS number); WT1050000 (RTECS number); 079011 (USEPA PC Code)

Trade Names: Aquarex ME; Dupanol WAQE; CT-535 (petition); Richonol AF; Stepanol ME; HSDB (2002a) and RTECS (2005) list over a hundred; additional trade names for SLS and mixtures containing SLS